For research use only. We do not sell to patients.

N-Desmethylclozapine-d8 hydrochloride

CAS No. : 2705402-91-9

Biological Activity：Desmethylclozapine-d8 (Norclozapine-d8) hydrochloride is the deuterium labeled N-Desmethylclozapine hydrochloride. N-Desmethylclozapine hydrochloride is a major active metabolite of the atypical antipsychotic drug Clozapine. N-Desmethylclozapine hydrochloride is a potent, allosteric and partial M1 receptors agonist (EC₅₀=115 nM) and is able to potentiate hippocampal N-methyl-d-aspartate (NMDA) receptor currents through M1 receptor activation. N-Desmethylclozapine hydrochloride is also a δ-opioid agonist^[2]^[3].

Research Area：Infection

Targets：Drug Metabolite|Opioid Receptor|mAChR|Virus Protease

Related Small Molecules:VU0357017 hydrochloride;Nicotinamide N-oxide;SRPIN340;ORL1 antagonist 1;ZIKV-IN-4;TBPB;Imidafenacin;Sabcomeline;Loperamide-d6 N-Oxide;Aminothiazole;Deltorphin 2 TFA;CYP2C9/CYP2C19-IN-1;4-Hydroxyphenylbutazone;Ampyrone;MK-6884;Resveratrol-3-O-sulfate sodium;Brompheniramine-d6 maleate;Sonidegib metabolite M48;Isonicotinic acid;Cycloguanil hydrochloride;L-Lysine

About Us:

MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use；
Structurally and synthetically diverse biologically active compounds；
roduct quality is the key to our success and we take pride in offering only the highest-grade products.；
We provide HNMR, LC-MS, HPLC, stability testing and activity assays of our products to clients.；
Product identity, quality, purity and activity are assured by our robust quality control programs and procedures.；

Structurally and synthetically diverse biologically active compounds；

Customized order volume ranging from milligrams to kilograms scale；

We provide customer-oriented services. To explore more, please contact us at [email protected]. Our team will gladly assist you.

Top Publications Citing Use of MCE Products