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Metformin
CAS No. : 657-24-9
Biological Activity：Metformin (1,1-Dimethylbiguanide) inhibits the mitochondrial respiratory chain in the liver, leading to activation of AMPK, enhancing insulin sensitivity for type 2 diabetes research. Metformin can cross the blood-brain barrier and triggers autophagy.
Research Area：Cancer|Metabolic Disease|Cardiovascular Disease
Targets：Autophagy|Mitophagy|AMPK
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Epigenetics Compound Library;Kinase Inhibitor Library;PI3K/Akt/mTOR Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Antiviral Compound Library;CNS-Penetrant Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Antioxidant Compound Library;Anti-diabetic Compound Library;Oxygen Sensing Compound Library;Anti-Cardiovascular Disease Compound Library;NMPA-Approved Drug Library;Glycolysis Compound Library;Cytoskeleton Compound Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Drug-Induced Liver Injury (DILI) Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Obesity Compound Library;Mitochondria-Targeted Compound Library;Lipid Metabolism Compound Library ;Glucose Metabolism Compound Library;Rare Diseases Drug Library;Children’s Drug Library;EMA-Approved Drug Library;FDA-Approved Anticancer Drug Library;Human Metabolite Library;Anti-Prostate Cancer Compound Library;Non-steroidal Anti-Inflammatory Compound Library;Anti-Aging Natural Product Library;
Related Small Molecules:AMPK activator 4;Curcumin;Melatonin-d3;ZLN024;YLF-466D;BAY-3827;Resveratrol;3α-Hydroxymogrol;Clioquinol;HTH-01-015;Betulinic acid;Matrine;TMPA;Sulfosuccinimidyl oleate;Hemin;Polydatin;AICAR;Cimiracemoside C;HL271
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