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M617

CAS No. : 860790-38-1

Biological Activity：M617 is a selective galanin receptor 1 (GAL1) agonist, with K_is of 0.23 and 5.71 nM for GAL1 and GAL2, respectively. M617, acting through its central GAL1, can promote GLUT4 expression and enhance GLUT4 content in the cardiac muscle of type 2 diabetic rats^[2].

Research Area：Cardiovascular Disease

Targets：Neuropeptide Y Receptor

Related Small Molecules:[D-Trp34]-Neuropeptide Y TFA;Pancreatic Polypeptide, human;Peptide YY (PYY), human;JNJ-5207787;[Leu31,Pro34]-Neuropeptide Y(human,rat) TFA;GR231118 TFA;Neuropeptide Y (human);RF9 hydrochloride;M1145;Galanin Receptor Ligand M35 TFA;Neuropeptide Y (3-36) (porcine);BMS-193885;CART (55-76), rat;Galantide;RFRP-3(human) TFA;BIBO3304 TFA;Neuropeptide SF(mouse,rat);Galanin (1-16), mouse, porcine, rat;FR252384;Galnon;[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide;CART (1-39), Human, Rat;Neuropeptide Y (13-36), amide, human;Neuropeptide S(Rat);Neuropeptide Y (22-36);Lu AA33810;Neuropeptide Y (3-36) (human, rat)

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