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Ivermectin
CAS No. : 70288-86-7
Biological Activity：Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin (MK-933) is a specific inhibitor of Impα/β1-mediated nuclear import and has potent antiviral activity towards both HIV-1 and dengue virus. It is a positive allosteric effector of P2X4 and the α7 neuronal nicotinic acetylcholine receptor (nAChRs). Ivermectin also inhibits bovine herpesvirus1 (BoHV-1) replication and inhibits BoHV-1 DNA polymerase nuclear import[2][3][4]. Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19[5].
Research Area：Infection|Cancer
Targets：Parasite|HSV|Autophagy|HIV|Mitophagy|Bacterial|Antibiotic|SARS-CoV
Related Screening Libraries:Natural Product Library Plus;Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Anti-Infection Compound Library;Natural Product Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Antiviral Compound Library;CNS-Penetrant Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Macrocyclic Compound Library;Antibacterial Compound Library;NMPA-Approved Drug Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Antibiotics Library;Drug-Induced Liver Injury (DILI) Compound Library;Antiparasitic Compound library;Microbial Metabolite Library;Mitochondria-Targeted Compound Library;Targeted Diversity Library;Children’s Drug Library;Anti-Cancer Natural Product Library;FDA-Approved Anticancer Drug Library;Nuclear Receptor Compound Library;
Related Small Molecules:(+)-Isopulegol;Sandramycin;LLO (91-99);Gepotidacin;Isoborneol;Oritavancin;Monascorubrin;SR9186;Antileishmanial agent-2;Azlocillin sodium salt;Herbimycin A;Antibacterial agent 45;Leucomycin;Isouvaretin;HIV-1 TAT (48-60);Antibacterial agent 99;Vidarabine monohydrate;Nafcillin
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