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Indotecan
CAS No. : 915303-09-2
Biological Activity：Indotecan (LMP-400), an indenoisoquinoline derivative, is a potent Topoisomerase I inhibitor, with IC50s of 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively. Indotecan prevents the relaxation of supercoiled DNA and can be used for the research of visceral leishmaniasis[2].
Research Area：Cancer|Infection
Targets：Topoisomerase
Related Screening Libraries:Clinical Compound Library Plus;Bioactive Compound Library Plus;
Related Small Molecules:Gepotidacin;Topoisomerase I/II inhibitor 3;(R)-Camptothecin-d5;Topoisomerase II inhibitor 8;FLT3-IN-13;TP3011;TAS-103 dihydrochloride;Rebeccamycin;AZD5099;TP0480066;Topoisomerase I inhibitor 4;Camptothecin;Corydamine;SW044248;9-Hydroxyellipticine hydrochloride;Flumequine-13C3;Trovafloxacin mesylate;Topoisomerase II inhibitor 12;Topoisomerase I inhibitor 3;Berberine sulfate;Betulinic acid;Hycanthone;Niranthin
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