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HWL-088

CAS No. : 2378617-96-8

Biological Activity：HWL-088 is a highly potent and orally active free fatty acid receptor 1 (FFA1/GPR40) agonist (EC₅₀ of 18.9 nM) with moderate PPARδ activity (EC₅₀ of 570.9 nM) . HWL-088 improves glucose and lipid metabolism, and has anti-diabetic effects^[2].

Research Area：Metabolic Disease

Targets：PPAR|Free Fatty Acid Receptor

Related Screening Libraries:Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;GPCR/G Protein Compound Library;Anti-Aging Compound Library;Anti-diabetic Compound Library;Oxygen Sensing Compound Library;Orally Active Compound Library;Transcription Factor-Targeted Library;Nuclear Receptor Compound Library;

Related Small Molecules:GW-1100;Falcarindiol;5-Aminosalicylic Acid-D3 hydrochloride;Retinoic acid;Grifolic acid;PPARγ agonist 7;Licarin B;Ginsenoside Rb2;Mifobate;Daidzein-d4;Ciglitazone;MK-886;AP5;CP-775146;FK614;GPR40 Activator 1;Muraglitazar;Magnolol;PPAR agonist 1;PPARα agonist 1;AM-1638;PPARγ phosphorylation inhibitor 1;GSK0660;Glabridin;CUDA;DC260126

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