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HIV-1 inhibitor-40
Biological Activity:HIV-1 inhibitor-40 (Compound 4ab) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) of HIV-1 with an EC50 of 1.9 nM. HIV-1 inhibitor-40 displays weak CYP sensitivity with IC50 values of 5.16 μM and 4.51 μM against CYP2C9 and CYP2C19, respectively. HIV-1 inhibitor-40 has no apparent in vivo acute toxicity.
Research Area:Infection
Targets:HIV|Cytochrome P450
Related Small Molecules:SR9186;AMG-208;HIV-1 TAT (48-60);Seletracetam lithium;HIV-IN-2;Triptonine B;CYP1B1-IN-1;CYP2C9/CYP2C19-IN-1;FC131;Peritassine A;Hypericin;Flavopiridol;TAT (48-57);FGI-106 tetrahydrochloride;(Z)-9-Propenyladenine;Apabetalone;Decanoyl-RVKR-CMK TFA;ONX-0914 TFA;Galeterone
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