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GSK3987
CAS No. : 264206-85-1
Biological Activity:GSK3987 is a pan LXRα/β agonist with EC50s of 50 nM, 40 nM for LXRα-SRC1 and LXRβ-SRC1, respectively. GSK3987 increases the expression of ABCA1 and SREBP-1c. GSK3987 induces cellular cholesterol efflux and triglyceride accumulation.
Research Area:Metabolic Disease
Targets:LXR
Related Screening Libraries:Bioactive Compound Library Plus;Metabolism/Protease Compound Library; Anti-Cancer Metabolism Compound Library;Lipid Metabolism Compound Library ;Nuclear Receptor Compound Library;
Related Small Molecules:XL041;BE1218;DMHCA;Saikosaponin A;27-Hydroxycholesterol;LXRβ agonist-3;RGX-104;24(S)-Hydroxycholesterol;SR9238;BMS-779788;SR9243;AZ876;T0901317;LXRβ agonist-2;GSK2033;LXR antagonist 2;LXR agonist 1;GW3965;LXR-623;Nagilactone B;LXR agonist 2;Rovazolac
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