For research use only. We do not sell to patients.

GSK143

CAS No. : 1240390-27-5

Biological Activity：GSK143 is an orally active and highly selective spleen tyrosine kinase (SYK) inhibitor with a pIC₅₀ of 7.5. GSK143 inhibits phosphorylated Erk (pErk: pIC₅₀=7.1). GSK143 reduces inflammation and prevents recruitment of immune cells in the intestinal muscularis in mice^[2]^[3].

Research Area：Cancer|Inflammation/Immunology

Targets：PERK|Syk

Related Small Molecules:Lanraplenib monosuccinate;AMG PERK 44;OXSI-2;GSK2656157;ONO-8130;SYK/JAK-IN-1;PERK-IN-3;PRT062607 Hydrochloride;MNS;TAK-659 hydrochloride;Syk Inhibitor II dihydrochloride dihydrate;VU0424465;Fostamatinib-d9;7DG;R406 free base;ML291;Fostamatinib Disodium;GSK2646264;Cevidoplenib;TAS05567;Midostaurin-d5;MEK/PI3K-IN-1;BAY 61-3606 dihydrochloride;Takeda-6D;GSK2606414;PERK-IN-5;Syk Kinase Peptide Substrate;PERK-IN-2

About Us:

MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use；
Structurally and synthetically diverse biologically active compounds；
roduct quality is the key to our success and we take pride in offering only the highest-grade products.；
We provide HNMR, LC-MS, HPLC, stability testing and activity assays of our products to clients.；
Product identity, quality, purity and activity are assured by our robust quality control programs and procedures.；

Structurally and synthetically diverse biologically active compounds；

Customized order volume ranging from milligrams to kilograms scale；

We provide customer-oriented services. To explore more, please contact us at [email protected]. Our team will gladly assist you.

Top Publications Citing Use of MCE Products