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Fingolimod hydrochloride
CAS No. : 162359-56-0
Biological Activity：Fingolimod hydrochloride (FTY720), an analog of sphingosine, is a potent sphingosine 1-phosphate (S1P) receptors modulator. Fingolimod hydrochloride is phosphorylated by sphingosine kinases, particularly by SK2, and then binds S1PR1, 3, 4, and 5. Fingolimod hydrochloride induces the internalization of S1P1, and consequently, inhibits S1P activity. Fingolimod hydrochloride also is a pak1 activator[4].
Research Area：Inflammation/Immunology|Cancer
Targets：PAK|LPL Receptor
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;GPCR/G Protein Compound Library;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Antiviral Compound Library;CNS-Penetrant Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Anti-diabetic Compound Library;Anti-COVID-19 Compound Library;Cytoskeleton Compound Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Neuroprotective Compound Library;Drug-Induced Liver Injury (DILI) Compound Library;Rare Diseases Drug Library;Children’s Drug Library;EMA-Approved Drug Library;FDA-Approved Anticancer Drug Library;Human Metabolite Library;Non-steroidal Anti-Inflammatory Compound Library;
Related Small Molecules:GNE 2861;GSK2018682;5-Aminosalicylic Acid-D3 hydrochloride;Ozanimod hydrochloride;BMS-986020 sodium;S1p receptor agonist 2;ONO-9780307;Siponimod hemifumarate;ZMF-10;S1P2 antagonist 1;AZ13705339;S1P1 agonist III;ZINC194100678;Ceralifimod;LCH-7749944;PAK4-IN-1;PAK4-IN-2;Ki16425;H2L 5765834;S1PR1 agonist 2;RP101442;S1PR1 agonist 1;CS-2100;ASP1126;IPA-3;1-Oleoyl lysophosphatidic acid
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