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Emapalumab
CAS No. : 1709815-23-5
Biological Activity:Emapalumab (NI-0501) is a humanized monoclonal IgG1 antibody that noncompetitively inhibits IFN-γ. Emapalumab binds with high affinity (Kd= 1.4 pM) to both free IFN-γ as well as IFN-γ bound to its receptor. Emapalumab can be used in research of hemophagocytic lymphohistiocytosis (HLH).
Research Area:Inflammation/Immunology
Targets:IFNAR
Related Small Molecules:AX-024;Cirsilineol;Ginsenoside F3;Deucravacitinib;TYK2-IN-12;Anti-Mouse IFNAR1 Antibody;GSK2245035;CP-28888;Delmitide;SM-276001;2′,3′-cGAMP sodium;Monalizumab;ODN 2216;ODN 1585;Fontolizumab;CCCP;Cyclo(L-Phe-L-Pro);RO8191;Sifalimumab;Cridanimod;ODN 6016;Anti-Mouse IFN gamma Antibody;ODN D-SL03;Vadimezan;VVD-118313;IFN alpha-IFNAR-IN-1
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