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DRF-1042

CAS No. : 200619-13-2

Biological Activity：DRF-1042 is an orally active derivative of Camptothecin. DRF-1042 acts to inhibit DNA topoisomerase I. DRF-1042 shows good anticancer activity against a panel of human cancer cell lines including multi-drug resistance (MDR) phenotype^[2].

Research Area：Cancer

Targets：Topoisomerase|ADC Cytotoxin

Related Screening Libraries:Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Toxins for Antibody-Drug Conjugate Research Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Orally Active Compound Library;Anti-Lung Cancer Compound Library;

Related Small Molecules:Sandramycin;Gepotidacin;Topoisomerase I/II inhibitor 3;(R)-Camptothecin-d5;Dolastatin 10;Topoisomerase II inhibitor 8;FLT3-IN-13;INX-SM-56;TP3011;TAS-103 dihydrochloride;DC10SMe;Rebeccamycin;Duocarmycin TM;Fmoc-MMAE;Taltobulin;N-Me-L-Ala-maytansinol;CC-885-CH2-PEG1-NH-CH3;AZD5099;TP0480066;Topoisomerase I inhibitor 4;Camptothecin;Corydamine;SW044248;Maytansinol

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