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Doxorubicin hydrochloride
CAS No. : 25316-40-9
Biological Activity：Doxorubicin (Hydroxydaunorubicin) hydrochloride, a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy[2][3].
Research Area：Cancer|Infection
Targets：Topoisomerase|Autophagy|ADC Cytotoxin|HIV|Mitophagy|Bacterial|Antibiotic|HBV|Apoptosis|AMPK
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Related Small Molecules:Physalin A;Bomedemstat ditosylate;Sandramycin;LLO (91-99);Gepotidacin;Enpp/Carbonic anhydrase-IN-1;GK563;AMPK activator 4;Calpeptin;Oritavancin;Lobetyolin;Monascorubrin;Azlocillin sodium salt;Herbimycin A;Antibacterial agent 45;Leucomycin;Isouvaretin;BJE6-106;Dinaciclib;HIV-1 TAT (48-60);Antibacterial agent 99
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