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CYM50308

CAS No. : 1345858-76-5

Biological Activity：CYM50308 (ML248) is a potent, selective and high affinity sphingosine-1-phosphate receptor 4 (S1P₄-R) agonist with an EC₅₀ of 56 nM. CYM50308 displays 37-fold more selective for S1P₄-R than S1P₅-R. CYM50308 has no activity at S1P₁-R, S1P₂-R and S1P₃-R subtypes at concentrations up to 25 μM.

Research Area：Cardiovascular Disease

Targets：LPL Receptor

Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Immunology/Inflammation Compound Library;Anti-Cardiovascular Disease Compound Library;Targeted Diversity Library;

Related Small Molecules:GSK2018682;Ozanimod hydrochloride;BMS-986020 sodium;S1p receptor agonist 2;ONO-9780307;Siponimod hemifumarate;S1P2 antagonist 1;S1P1 agonist III;Ceralifimod;Ki16425;H2L 5765834;S1PR1 agonist 2;RP101442;S1PR1 agonist 1;CS-2100;ASP1126;1-Oleoyl lysophosphatidic acid;Ex26;RP-001 hydrochloride;VPC 23019;CYM-5541;LPA1 receptor antagonist 1;Autotaxin-IN-6;Zectivimod;CYM5442 hydrochloride;PF-543 Citrate;LPA2 antagonist 1;LPA2 antagonist 2

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