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CU-115
CAS No. : 2471982-20-2
Biological Activity：CU-115 is a potent TLR8 antagonist (IC50=1.04 µM), and shows selective for TLR8 over TLR7 (IC50=>50 µM). CU-115 decreases TNF-α and IL-1β production activated by R-848 in THP-1 cells.
Research Area：Inflammation/Immunology
Targets：Toll-like Receptor (TLR)
Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Small Molecule Immuno-Oncology Compound Library;Antioxidant Compound Library;Oxygen Sensing Compound Library;Pyroptosis Compound Library;Antidepressant Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:C29;TMX-201;RS 09;ODN 20844;TLR7/8-IN-1;TLR8 agonist 5;Sulfo-ara-F-NMN;TLR7/8 antagonist 1;Gardiquimod;PF-4878691;Tri(TLR4-IN-C34-PEG2-amide-PEG1)-amide-C3-COOH;Pepinh-TRIF TFA;Afimetoran;Schaftoside;ODN 2088;CU-CPT22;UC-1V150;Diprovocim-X;CL264;MMG-11 quarterhydrate;CU-CPT 4a;TLR7/8 agonist 4;SM-324405;Enpatoran
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