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COX-2/sEH-IN-1
CAS No. : 2474977-38-1
Biological Activity：COX-2/sEH-IN-1 (Compound 9c) is an orally active, dual COX-2 and sEH (soluble epoxide hydrolase) inhibitor with IC50 values of 1.24 µM and 0.40 nM against COX-2 and sEH, respectively. COX-2/sEH-IN-1 shows improved anti-inflammatory activity and highly reduced cardiovascular risks.
Research Area：Cardiovascular Disease
Targets：Epoxide Hydrolase|COX
Related Small Molecules:Akt/NF-κB/JNK-IN-1;COX-2/5-LOX-IN-3;SWE101;Ampyrone;COX-2-IN-24;Zaltoprofen-d7;sEH inhibitor-11;(Rac)-EC5026;α-Vitamin E-d6;1-Hydroxy-ibuprofen;Asaraldehyde;(-)-Epicatechin;20(S)-Ginsenoside Rg3;Ginsenoside Rd;Nimesulide D5;COX-2/5-LOX-IN-1;GSK2256294A;S-(+)-Marmesin;Tazofelone;Catechin-13C3;Diclofenac-d4;Proglumetacin;Ethoxycoronarin D;Phenidone;BI-1935;Iguratimod
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