For research use only. We do not sell to patients.

Corticosterone

CAS No. : 50-22-6

Biological Activity：Corticosterone (17-Deoxycortisol) is an orally active and adrenal cortex-produced glucocorticoid, which plays an important role in regulating neuronal functions of the limbic system (including hippocampus, prefrontal cortex, and amygdala). Corticosterone increases the Rab-mediated AMPAR membrane traffic via SGK-induced phosphorylation of GDI. Corticosterone also interferes with the maturation of dendritic cells and shows a good immunosuppressive effect^[2]^[3]^[4].

Research Area：Endocrinology|Inflammation/Immunology|Neurological Disease

Targets：Glucocorticoid Receptor|Endogenous Metabolite|iGluR

Related Screening Libraries:Natural Product Library Plus;Drug Repurposing Compound Library Plus;Clinical Compound Library Plus; Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Membrane Transporter/Ion Channel Compound Library;Metabolism/Protease Compound Library;Neuronal Signaling Compound Library;Natural Product Library;Clinical Compound Library;Human Endogenous Metabolite Compound Library;Drug Repurposing Compound Library;Lipid Compound Library;Endocrinology Compound Library;Anti-COVID-19 Compound Library;Medicine Food Homology Compound Library;Orally Active Compound Library;Neurotransmitter Receptor Compound Library;Traditional Chinese Medicine Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Food-Sourced Compound Library ;Anti-inflammatory Traditional Chinese Medicine Active Compound Library;Human Metabolite Library;Nuclear Receptor Compound Library;

Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Nicotinamide N-oxide;3-Hydroxyglutaric acid-d5;DPPC-d62;SDMA-d6;2-Mercaptobenzothiazole;N-Acetyl-L-glutamic acid-d5;(3R,5S)-3-Hydroxy Cotinine-d3;Biliverdin hydrochloride;D-Glucose-13C,d1-3;2,3-Diaminopropionic acid hydrochloride;Docosanoic acid-d3;Choline-d6 chloride;Pregnenolone monosulfate sodium;25-Hydroxycholesterol-d6;Pyrroloquinoline quinone;Roridin L2;NAPQI;Imidazole

About Us:

MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use；
Structurally and synthetically diverse biologically active compounds；
roduct quality is the key to our success and we take pride in offering only the highest-grade products.；
We provide HNMR, LC-MS, HPLC, stability testing and activity assays of our products to clients.；
Product identity, quality, purity and activity are assured by our robust quality control programs and procedures.；

Structurally and synthetically diverse biologically active compounds；

Customized order volume ranging from milligrams to kilograms scale；

We provide customer-oriented services. To explore more, please contact us at [email protected]. Our team will gladly assist you.

Top Publications Citing Use of MCE Products