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BMS-309403 sodium
Biological Activity：BMS-309403 sodium is a potent, orally active, and selective adipocyte fatty acid binding protein (also known as FABP4, aP2) inhibitor, with Kis of <2, 250, and 350 nM for FABP4, FABP3, and FABP5, respectively. BMS-309403 sodium interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS-309403 sodium improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells[2][3].
Research Area：Metabolic Disease|Cardiovascular Disease
Targets：FABP
Related Screening Libraries:Bioactive Compound Library Plus;Metabolism/Protease Compound Library;Anti-Cardiovascular Disease Compound Library;Orally Active Compound Library;Lipid Metabolism Compound Library ;Human Metabolite Library;
Related Small Molecules:FABP-IN-1;FABP5-IN-1;BMS-309403;HTS01037;FABPs ligand 6
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
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