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AWZ1066S

CAS No. : 2239272-16-1

Biological Activity：AWZ1066S is a highly potent, specific and orally active anti-Wolbachia agent with EC₅₀ value of 121 nM. AWZ1066S also is a weak CYP2C9 inhibitor and a weak CYP3A4 inducer with IC₅₀ values of 9.7 μM and 37 uM, respectively. AWZ1066S can be used for the research of tropical diseases such as Onchocerciasis (river blindness) and lymphatic filariasis (elephantiasis) .

Research Area：Infection

Targets：Parasite

Related Screening Libraries:Clinical Compound Library Plus;Bioactive Compound Library Plus;Anti-Infection Compound Library;Clinical Compound Library;Orally Active Compound Library;Antiparasitic Compound library;

Related Small Molecules:(+)-Isopulegol;SR9186;Antileishmanial agent-2;Azlocillin sodium salt;SQ109;Trypanothione synthetase-IN-3;Pyrantel;α-Terpinene;Dehydrocorydaline;Niclosamide monohydrate;Febrifugine dihydrochloride;Antimalarial agent 15;Cycloguanil hydrochloride;Anti-infective agent 6;Morantel tartrate;Sulfiram;UCB7362;Retro-2;PfDHODH-IN-2;ML251

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