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Aurothioglucose
CAS No. : 12192-57-3
Biological Activity:Aurothioglucose (Gold thioglucose), containing monovalent gold ion, is a potent active-site inhibitor of TrxR1 (thioredoxin reductase 1), with an IC50 of 65 nM. Aurothioglucose inhibits the DNA binding of NF-κB in vitro. Aurothioglucose shows anti-HIV and anti-rheumatic activities[2].
Research Area:Cancer|Infection|Inflammation/Immunology
Targets:NF-κB|Reactive Oxygen Species|HIV
Related Screening Libraries:Covalent Screening Library Plus;Bioactive Compound Library Plus;Anti-Infection Compound Library;Immunology/Inflammation Compound Library;Metabolism/Protease Compound Library;NF-κB Signaling Compound Library;Stem Cell Signaling Compound Library;Anti-Cancer Compound Library;Antiviral Compound Library;Anti-Aging Compound Library;Covalent Screening Library;Antioxidant Compound Library;Differentiation Inducing Compound Library;Oxygen Sensing Compound Library;Ferroptosis Compound Library;Pyroptosis Compound Library;FDA Approved & Pharmacopeial Drug Library;Anti-Breast Cancer Compound Library;Drug-Induced Liver Injury (DILI) Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Obesity Compound Library;Mitochondria-Targeted Compound Library;Transcription Factor-Targeted Library;Anti-Liver Cancer Compound Library ;Antidepressant Compound Library;Anti-Prostate Cancer Compound Library;Cancer Stem Cells Compound Library;
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