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ATX inhibitor 15
CAS No. : 2484811-52-9
Biological Activity：ATX inhibitor 15 (compound 30), a indole-based carbamate derivative, is a potent autotaxin (ATX) inhibitor with an IC50 of 2.17 nM. ATX inhibitor 15 inhibits in vivo ATX and the gene expression of pro-fibrotic factors. ATX inhibitor 15 has lung protection effects in Bleomycin challenged mice lung fibrosis model.
Research Area：Inflammation/Immunology
Targets：Phosphodiesterase (PDE)
Related Small Molecules:Senazodan hydrochloride;(E/Z)-HA155;Enpp/Carbonic anhydrase-IN-1;ATX inhibitor 22;Carbazeran citrate;Bay 60-7550;BC11-38;Deltarasin hydrochloride;Glaucine;Ziritaxestat;Udenafil-d7;D159687;ITI-214;PDE10-IN-5;ICI 153110;Furamidine dihydrochloride;ML-030;PDE4-IN-10;Mirodenafil-d7 dihydrochloride;PDE1-IN-4;PDE4B-IN-3;Cirsimarin;PF-03049423;IBMX;Pimobendan;Gisadenafil besylate;S32826 disodium
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