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AS-604850
CAS No. : 648449-76-7
Biological Activity：AS-604850 is a potent, selective and ATP-competitive PI3Kγ inhibitor with an IC50 value of 0.25 μM and a Ki value of 0.18 μM. AS-604850 shows isoform selective inhibitor of PI3Kγ with over 30-fold selectivity for PI3Kδ and β, and 18-fold selectivity over PI3Kα, respectively.
Research Area：Cancer
Targets：PI3K
Related Screening Libraries:Bioactive Compound Library Plus;Kinase Inhibitor Library;PI3K/Akt/mTOR Compound Library;Stem Cell Signaling Compound Library;Anti-Cancer Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Differentiation Inducing Compound Library;Oxygen Sensing Compound Library;Glycolysis Compound Library;Cytoskeleton Compound Library;Anti-Breast Cancer Compound Library;Anti-Lung Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Obesity Compound Library;Angiogenesis-Related Compound Library;Glucose Metabolism Compound Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:Umbralisib hydrochloride;Topoisomerase I/II inhibitor 3;Rigosertib sodium;Tenalisib R Enantiomer;PI3kδ inhibitor 1;PI3K/VEGFR2-IN-1;1,3-Dicaffeoylquinic acid;PI3Kδ-IN-1;PI-103-d8;PI3Kα-IN-8;PI-103 Hydrochloride;IC-87114;PI3K/mTOR Inhibitor-6;PI3K-IN-10;SF2523;PI3K-IN-29;PI3K/mTOR Inhibitor-1;PI3K-IN-26;GSK-F1;Serabelisib;Amdizalisib;Glaucocalyxin A;PI3K/AKT-IN-2;PIK-294;CAL-130 Hydrochloride;YS-49;hSMG-1 inhibitor 11e
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