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Anti-inflammatory agent 22
CAS No. : 2721484-76-8
Biological Activity：Anti-inflammatory agent 22 (compound 14a) is an orally active anti-inflammatory agent. Anti-inflammatory agent 22 inhibits LPS-induced TNF-α production with an IC50 value of 14.6 μM. Anti-inflammatory agent 22 has preventive effects on lymphedematous tissue via suppression of adipogenesis. Anti-inflammatory agent 22 suppresses limb lymphedema volume in mice.
Research Area：Inflammation/Immunology
Targets：TNF Receptor
Related Small Molecules:Akt/NF-κB/JNK-IN-1;AX-024;QNZ;Sinulatumolin E;Epobis;Mulberroside A;Sinulatumolin D;PDE4-IN-10;Ginsenoside Rc;TIC10;Teneliximab;Loganic acid 6′-O-β-D-glucoside;VGX-1027;D-Trimannuronic acid;DCVC;Gamma-glutamylcysteine TFA;Varlilumab;Sinulatumolin C;Thunbergol;Roquinimex;Semapimod tetrahydrochloride;GSK2245035;R-7050;Sinensetin-d3;TNF-α (31-45), human TFA;Cynaropicrin
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