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ADL-5859
CAS No. : 850173-95-4
Biological Activity：ADL-5859 (compound 20) is a selective and orally active δ opioid receptor (DOR) agonist with an Ki and an EC50 value of 0.84 and 20 nM, respectively. ADL-5859 also shows inhibitory activity to hERG channel with an IC50 value of 78 μM. ADL-5859 can be used for the research of pain[2].
Research Area：Inflammation/Immunology|Neurological Disease
Targets：Opioid Receptor|Potassium Channel|Cytochrome P450
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Immunology/Inflammation Compound Library;Membrane Transporter/Ion Channel Compound Library;Metabolism/Protease Compound Library;Neuronal Signaling Compound Library;Clinical Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library; Antioxidant Compound Library;Oxygen Sensing Compound Library;Orally Active Compound Library;Neurotransmitter Receptor Compound Library;Anti-Alzheimer’s Disease Compound Library;Neurodegenerative Disease-related Compound Library;Targeted Diversity Library;Antidepressant Compound Library;Potassium Channel Compound Library;
Related Small Molecules:ORL1 antagonist 1;SR9186;AMG-208;Kv3 modulator 2;Loperamide-d6 N-Oxide;Deltorphin 2 TFA;CYP1B1-IN-1;CYP2C9/CYP2C19-IN-1;Brompheniramine-d6 maleate;Hypericin;Pinacidil;AMP-PNP tetralithium;IK1 inhibitor PA-6;Nalfurafine;VU590;Galeterone;Ranitidine;Domiphen bromide;Mesoridazine benzenesulfonate;Bergapten;Tetrandrine;20(S)-Ginsenoside Rg3;β-Lipotropin (60-65)
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