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Actinonin
CAS No. : 13434-13-4
Biological Activity：Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces. Actinonin inhibits aminopeptidase M, aminopeptidase N and leucine aminopeptidase. Actinonin is a potent reversible peptide deformylase (PDF) inhibitor with a Ki of 0.28 nM. Actinonin also inhibits MMP-1, MMP-3, MMP-8, MMP-9, and hmeprin α with Ki values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin is an apoptosis inducer. Actinonin has antiproliferative and antitumor activities[2][3][4][5].
Research Area：Cancer|Infection
Targets：Bacterial|Antibiotic|MMP|Apoptosis|Aminopeptidase
Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Anti-Infection Compound Library;Apoptosis Compound Library;Metabolism/Protease Compound Library;Natural Product Library;Anti-Cancer Compound Library;Differentiation Inducing Compound Library;Antibacterial Compound Library;Antibiotics Library;Anti-Pancreatic Cancer Compound Library;Microbial Metabolite Library;Angiogenesis-Related Compound Library;Anti-Cancer Natural Product Library;Protein-protein Interaction Inhibitor Library;Anti-Pulmonary Fibrosis Compound Library;
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