4-Hydroxyatomoxetine

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4-Hydroxyatomoxetine

CAS No. : 435293-66-6

Biological Activity:4-Hydroxyatomoxetine is an active metabolite of Atomoxetine. 4-Hydroxyatomoxetine is metabolized by the enzyme cytochrome P450 2D6 (CYP2D6). Atomoxetine hydrochloride is a potent and selective noradrenalin re-uptake inhibitor (Ki values are 5 nM, 77 nM and 1451 nM for inhibition of radioligand binding to human NET, SERT and DAT respectively)[2].

Research Area:Neurological Disease

Targets:Adrenergic Receptor

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