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3′,4′-Dimethoxyflavone
CAS No. : 4143-62-8
Biological Activity：3′,4′-Dimethoxyflavone is a lipophilic flavone, can be isolated from the leaves of Primula veris. 3′,4′-Dimethoxyflavone can reduce the synthesis and accumulation of PARP and protect cortical neurones against cell death induced by Parthanatos. 3′,4′-Dimethoxyflavone is also an aryl hydrocarbon receptor antagonist in human breast cancer cells. 3′,4′-Dimethoxyflavone can promote the proliferation of human hematopoietic stem cells. 3′,4′-Dimethoxyflavone has various biological activities, including antioxidant, anti-cancer, anti-inflammatory, anti-atherogenic, hypolipidaemic, and neuroprotective or neurotrophic effects[2][3][4].
Research Area：Cancer|Inflammation/Immunology|Neurological Disease|Cardiovascular Disease
Targets：PARP|Reactive Oxygen Species|Aryl Hydrocarbon Receptor
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