1-Methyl-2-undecyl-4(1H)-quinolone

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1-Methyl-2-undecyl-4(1H)-quinolone

CAS No. : 59443-02-6

Biological Activity:1-Methyl-2-undecyl-4(1H)-quinolone is a potent, irreversible and selective inhibitor of type B monoamine oxidase (MAO-B). 1-Methyl-2-undecyl-4(1H)-quinolone shows a selective inhibition of MAO-B activity with the IC50 and Ki values of 15.3 μM and 9.91 μM, respectively, but did not inhibit type A MAO (MAO-A) activity. Methyl-2-undecyl-4(1H)-quinolone, as a quinolone alkaloid, is isolated from fresh leaves and fruits of Evodia rutaecarpa HOOK. f. et THOMS[2].

Research Area:Neurological Disease

Targets:Monoamine Oxidase

Related Small Molecules:PXS-4728A;Hypericin;Simtuzumab;SSAO inhibitor-1;5-HT6R/MAO-B modulator 1;Glicoricone;MAO-B-IN-1;LOX-IN-3;LSD1-IN-16;β-Aminopropionitrile;Lazabemide;Monoamine oxidase/Aromatase-IN-1;PXS-5120A;Pirlindole mesylate;SSAO inhibitor-3;Ladostigil hemitartrate;MAO-B-IN-12;Pheniprazine;PF9601N

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