Trk-IN-7

For research use only. We do not sell to patients.

Trk-IN-7

Biological Activity：Trk-IN-7 (compound I-6) is a potent TRK inhibitor with IC50s of ranging from 0.25-10 nM for TRKA, TRKB and TRKC, respectively. Trk-IN-7 shows inhibition against EML4-ALK (IC50<15 nM) ALK G1202R, ALK C1156Y, ALK R1275Q, ALK F1174L, ALK L1197M, and ALK G1269A (IC50=5-50 nM).

Research Area：Cancer

Targets：Trk Receptor

Related Small Molecules:hTrkA-IN-1;IHMT-TRK-284;ANA-12;Larotrectinib sulfate;N-Acetyl-5-hydroxytryptamine;LM22B-10;D5261;N-Acetyl-5-hydroxytryptamine-d3;7,8-Dihydroxyflavone;TRK-IN-18;TRK-IN-12;CH7057288;Entrectinib;Pan-Trk-IN-3;ONO-7475;AZ-23;Trk-IN-6;GNF-5837;Cyclotraxin B;TrkA-IN-1;PF-06737007;TRK II-IN-1;Trk-IN-10;Trk-IN-9;Trk-IN-1;Sacibertinib;Pan-Trk-IN-2;TRK-IN-13

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