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THK-5470
CAS No. : 2410554-04-8
Biological Activity：THK-5470, a monoamine oxidase-B (MAO-B) imaging probe, could be used for neurological diseases study. THK-5470 shows remarkably high binding affinity against MAO-B with an IC50 value of 4.2 nM, low binding affinity against tau with an IC50 value of 4462 nM. THK-5470 has high selective binding property and high affinity (from patent EP2019-846498).
Research Area：Neurological Disease
Targets：Monoamine Oxidase
Related Screening Libraries:Bioactive Compound Library Plus;Neuronal Signaling Compound Library;Neurodegenerative Disease-related Compound Library;Mitochondria-Targeted Compound Library;
Related Small Molecules:PXS-4728A;Hypericin;Simtuzumab;SSAO inhibitor-1;5-HT6R/MAO-B modulator 1;Glicoricone;MAO-B-IN-1;LOX-IN-3;LSD1-IN-16;β-Aminopropionitrile;Lazabemide;Monoamine oxidase/Aromatase-IN-1;PXS-5120A;Pirlindole mesylate;SSAO inhibitor-3;Ladostigil hemitartrate;MAO-B-IN-12;Pheniprazine;PF9601N
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