(S)-IDO1-IN-5

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(S)-IDO1-IN-5

CAS No. : 2166616-76-6

Biological Activity:(S)-IDO1-IN-5 (Example 1B) is an active S-isomer of IDO1-IN-5. (S)-IDO1-IN-5 binds to IDOL with an IC50 value less than 1.5 µΜ. IDO1-IN-5 is a potent, selective and brain penetrated inhibitor of Indoleamine 2,3-Dioxygenase 1 (IDO1) activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1[2].

Research Area:Cancer

Targets:Indoleamine 2,3-Dioxygenase (IDO)

Related Screening Libraries:Covalent Screening Library Plus;Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Metabolism/Protease Compound Library;Anti-Cancer Compound Library;Small Molecule Immuno-Oncology Compound Library;Covalent Screening Library;

Related Small Molecules:IDO1-IN-14;Coptisine Sulfate;Coptisine chloride;IACS-8968;Indoximod;IDO-IN-12;IDO1-IN-16;IDO-IN-14;(S)-Indoximod-d3;IDO1-IN-5;IDO1-IN-18;Palmatine;IDO1-IN-2;IDO5L;IDO-IN-8;BMS-986242;IDO1-IN-12;IDO1/2-IN-1;GNF-PF-3777;Linrodostat;ZC0109;IDO1-IN-15;NLG802;NU223612;IDO1/TDO-IN-4;IDO1/TDO-IN-1;IDO1-IN-19

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