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Polyphyllin VI
CAS No. : 55916-51-3
Biological Activity:Polyphyllin VI, an active saponin, possess anti-cancer activities. Polyphyllin VI induces G2/M cell cycle arrest and triggers apoptosis[2]. Polyphyllin VI induces caspase-1-mediated pyroptosis via the induction of ROS/NF-κB/NLRP3/GSDMD signal axis in non-small cell lung cancer[3].
Research Area:Cancer
Targets:Pyroptosis|Apoptosis
Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Apoptosis Compound Library;Immunology/Inflammation Compound Library;NF-κB Signaling Compound Library;Natural Product Library;Anti-Cancer Compound Library;Glycoside Compound Library;Medicine Food Homology Compound Library;Traditional Chinese Medicine Active Compound Library;Anti-Lung Cancer Compound Library; Anti-Cancer Natural Product Library;Antidepressant Compound Library;Anti-inflammatory Traditional Chinese Medicine Active Compound Library;Plant-Sourced Natural Product Library;
Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis inducer 9;Bafetinib;Cyclovirobuxine D;STAT3-IN-10;Rigosertib sodium
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