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PI3K-IN-28
CAS No. : 2747100-02-1
Biological Activity：PI3K-IN-28 (Compound 6c) is a potent inhibitor of PI3K. PI3K-IN-28 displays the most potent activity with lower toxic effects on MCF-10a. PI3K-IN-28 displays half-maximal inhibitory concentration (IC50, μM) values of 5.8, 2.3, and 7.9. PI3K-IN-28 is the most potent one with a selectivity index (SI) of 39 and is considered as a latent lead for further optimization of anticancer agents.
Research Area：Cancer
Targets：PI3K
Related Small Molecules:Umbralisib hydrochloride;Topoisomerase I/II inhibitor 3;Rigosertib sodium;Tenalisib R Enantiomer;PI3kδ inhibitor 1;PI3K/VEGFR2-IN-1;1,3-Dicaffeoylquinic acid;PI3Kδ-IN-1;PI-103-d8;PI3Kα-IN-8;PI-103 Hydrochloride;IC-87114;PI3K/mTOR Inhibitor-6;PI3K-IN-10;SF2523;PI3K-IN-29;PI3K/mTOR Inhibitor-1;PI3K-IN-26;GSK-F1;Serabelisib;Amdizalisib;Glaucocalyxin A;PI3K/AKT-IN-2;PIK-294;CAL-130 Hydrochloride;YS-49;hSMG-1 inhibitor 11e
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