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Oxybutynin chloride
CAS No. : 1508-65-2
Biological Activity：Oxybutynin chloride is an oral active and competitive mAChR antagonist with Kis of 14.3 and 5.55 nM for specific [3H]NMS binding in the mouse bladder and cerebral cortex, respectively. Oxybutynin chloride inhibits vascular Kv channels in a manner independent of anticholinergic effect, with an IC50 value of 11.51 μM. Oxybutynin chloride reduces muscle spasm in the bladder and urinary tract, can be used in study of overactive bladder syndrome (OAB)[2].
Research Area：Neurological Disease
Targets：mAChR|Potassium Channel
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Membrane Transporter/Ion Channel Compound Library;Neuronal Signaling Compound Library;FDA-Approved Drug Library;CNS-Penetrant Compound Library;Drug Repurposing Compound Library;Orally Active Compound Library;Neurotransmitter Receptor Compound Library;FDA Approved & Pharmacopeial Drug Library;Anti-Alzheimer’s Disease Compound Library;Drug-Induced Liver Injury (DILI) Compound Library;Anti-Parkinson’s Disease Compound Library;Neurodegenerative Disease-related Compound Library;Rare Diseases Drug Library;Children’s Drug Library;EMA-Approved Drug Library;Potassium Channel Compound Library;Human Metabolite Library;Anti-Prostate Cancer Compound Library;
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