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N-Ethylmaleimide
CAS No. : 128-53-0
Biological Activity：N-Ethylmaleimide (NEM) derives from maleic acid, it can alkylates free sulfhydryl. N-Ethylmaleimide is an irreversible cysteine protease inhibitor. N-ethylmaleimide specific inhibits phosphate transport in mitochondria. N-Ethylmaleimide inhibits prolyl endopeptidase with an IC50 value of 6.3 μM. N-Ethylmaleimide can be used to modify cysteine residues in proteins and peptides[2][3].
Research Area：Others
Targets：Cathepsin|Deubiquitinase|Apoptosis
Related Screening Libraries:Covalent Screening Library Plus;Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Apoptosis Compound Library;Cell Cycle/DNA Damage Compound Library;Metabolism/Protease Compound Library;Clinical Compound Library;Fragment Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Covalent Screening Library;Ubiquitination Compound Library;Anti-COVID-19 Compound Library;FDA Approved & Pharmacopeial Drug Library;Angiogenesis-Related Compound Library;Human Metabolite Library;
Related Small Molecules:Physalin A;SJB3-019A;Bomedemstat ditosylate;SJB2-043;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;USP7-IN-1;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis inducer 9;Bafetinib
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