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MRT67307

CAS No. : 1190378-57-4

Biological Activity：MRT67307 is a dual inhibitor of the IKKε and TBK-1 with IC₅₀s of 160 and 19 nM, respectively. MRT67307 also inhibits ULK1 and ULK2 with IC₅₀s of 45 and 38 nM, respectively. MRT67307 also blocks autophagy in cells^[2].

Research Area：Cancer|Inflammation/Immunology

Targets：Autophagy|ULK|IKK

Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;NF-κB Signaling Compound Library;Stem Cell Signaling Compound Library;Anti-Cancer Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Differentiation Inducing Compound Library;Anti-Liver Cancer Compound Library ;Anti-Prostate Cancer Compound Library;

Related Small Molecules:DB0614;PS-1145;NF-κB-IN-1;Resveratrol;IKK-IN-3;Anti-inflammatory agent 6;PF-184;BOT-64;Siegesbeckialide I;LY2409881;(Rac)-BL-918;Tizoxanide;GW406108X;Bay 65-1942 (R form);MRT68921 dihydrochloride;IKK 16;SBI-0206965;AZD3264;Chicanine;Resveratrol-d4;IMD-0560;GSK319347A;IKK-IN-1;Ertiprotafib;ACHP Hydrochloride;IKK2-IN-3

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