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Latrunculin A
CAS No. : 76343-93-6
Biological Activity：Latrunculin A (LAT-A), found in the red sea sponge Latrunculia magnifica, is a G-actin polymerization inhibitor. Latrunculin A binds to actin monomers and inhibits polymerization of actin with Kds of 0.1, 0.4, 4.7 μM and 0.19 μM for ATP-actin, ADP-Pi-actin, ADP-actin and G-actin, respectively. Latrunculin A has effective anti-metastatic properties for cancer research. Latrunculin A blocks cell migration[2][3][4][5][6].
Research Area：Cancer
Targets：Arp2/3 Complex
Related Small Molecules:Wiskostatin;CK-869;Jasplakinolide;Dihydrocytochalasin B;SMIFH2;CK-636;Cytochalasin B;187-1, N-WASP inhibitor TFA;Phalloidin-TRITC;CK-666;Cytochalasin D;Phallacidin;19-O-Acetylchaetoglobosin A;LKKTETQ
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