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K00546
CAS No. : 443798-47-8
Biological Activity：K00546 is a potent CDK1 and CDK2 inhibitor with IC50s of 0.6 nM and 0.5 nM for CDK1/cyclin B and CDK2/cyclin A, respectively. K00546 is also a potent CDC2-like kinase 1 (CLK1) and CLK3 inhibitor with IC50s of 8.9 nM and 29.2 nM, respectively[2][3].
Research Area：Cancer
Targets：CDK|VEGFR|GSK-3
Related Screening Libraries:Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Kinase Inhibitor Library;PI3K/Akt/mTOR Compound Library;Protein Tyrosine Kinase Compound Library;Stem Cell Signaling Compound Library;Wnt/Hedgehog/Notch Compound Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Differentiation Inducing Compound Library;Reprogramming Compound Library;Oxygen Sensing Compound Library;Glycolysis Compound Library;Cytoskeleton Compound Library;Anti-Alzheimer’s Disease Compound Library;Anti-Breast Cancer Compound Library;Anti-Lung Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Neurodegenerative Disease-related Compound Library;Anti-Obesity Compound Library;Angiogenesis-Related Compound Library;Glucose Metabolism Compound Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;Antidepressant Compound Library;Anti-Pulmonary Fibrosis Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:(Z)-FeCP-oxindole;DB0614;TCS2002;Dinaciclib;VEGFR-2-IN-24;AR-A014418;BMS-690514;SNS-032;CC-671;PROTAC VEGFR-2 degrader-2;(E/Z)-Zotiraciclib;CDK1-IN-4;Henatinib;CCT-251921;BS-181;Samuraciclib hydrochloride hydrate;PI3K/VEGFR2-IN-1;T025;Flavopiridol;CDK8-IN-3;CDK9-IN-12;FLT3/CDK4-IN-1;GFB-12811;GSK 3 Inhibitor IX;Eciruciclib
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