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Ethyl azetidine-3-carboxylate hydrochloride

CAS No. : 405090-31-5

Biological Activity：Ethyl azetidine-3-carboxylate hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Ethyl azetidine-3-carboxylate hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs^[2]

Research Area：Cancer

Targets：PROTAC Linkers|ADC Linker

Related Screening Libraries:Fragment Library;

Related Small Molecules:N-(Mal-PEG6)-N-bis(PEG7-TCO);Propargyl-PEG2-CH2COOH;NHS ester-PEG10-COOH;Tos-PEG5-Boc;Bis-PEG6-NHS ester;Azide-PEG12-alcohol;PDdEC-NB;Fmoc-PEG6-NHS ester;Fmoc-D-Trp(Boc)-OH;Boc-C1-PEG3-C4-OBn;Boc-NH-PEG8-C2-Br;Propargyl-PEG14-Boc;m-PEG21-OH;Bromo-PEG3-THP;m-PEG8-Ms;Bis-PEG10-NHS ester;TCO-PEG3-acid;m-PEG8-DBCO;Azide-PEG6-Tos;Acid-PEG3-C2-Boc;m-PEG-mal (MW 2000);Benzyl-PEG7-t-butyl ester;Boc-Pip-alkyne-Ph-COOH;Biotin-PEG2-C6-azide;Bis-PEG4-acid;Active-mono-sulfone-PEG8-acid;Br-PEG6-C2-NHBoc;HO-PEG8-CH2COOH;NH2-PEG4-CH2CH2COOH;N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester

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