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Brefeldin A
CAS No. : 20350-15-6
Biological Activity:Brefeldin A (BFA) is a lactone antibiotic and a specific inhibitor of protein trafficking. Brefeldin A blocks the transport of secreted and membrane proteins from endoplasmic reticulum to Golgi apparatus[2]. Brefeldin A is also an autophagy and mitophagy inhibitor[3]. Brefeldin A is a CRISPR/Cas9 activator[5]. Brefeldin A inhibits HSV-1 and has anti-cancer activity[5].
Research Area:Cancer|Infection
Targets:CRISPR/Cas9|HSV|Autophagy|Mitophagy|Bacterial|Antibiotic
Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Anti-Infection Compound Library;Cell Cycle/DNA Damage Compound Library;Natural Product Library;Anti-Cancer Compound Library;Antiviral Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Macrocyclic Compound Library;Antibacterial Compound Library;Medicine Food Homology Compound Library;Traditional Chinese Medicine Active Compound Library;Antibiotics Library;Anti-Breast Cancer Compound Library;Microbial Metabolite Library;Mitochondria-Targeted Compound Library;Anti-Cancer Natural Product Library;Antiviral Traditional Chinese Medicine Active Compound Library;
Related Small Molecules:Sandramycin;LLO (91-99);Gepotidacin;Isoborneol;Oritavancin;Monascorubrin;Azlocillin sodium salt;Herbimycin A;Antibacterial agent 45;Leucomycin;Isouvaretin;Antibacterial agent 99;Vidarabine monohydrate;Nafcillin;Antitubercular agent-28;Ochromycinone;Staurosporine;Nucleocidin;(±)-Leucine-13C-1;Ciclopirox-d11;Ciclopirox olamine
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