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[Ala17]-MCH TFA
Biological Activity:[Ala17]-MCH TFA, a MCH analogue (HY-P1525A), is a selective ligand for MCHR1 (Ki=0.16 nM) over MCHR2 (Ki=34 nM). [Eu3+ chelate-labeled [Ala17]-MCH shows high affnity for MCHR1 (Kd=0.37 nM) while has little demonstrable binding affnity for MCHR2.
Research Area:Metabolic Disease
Targets:MCHR1 (GPR24)
Related Small Molecules:SB-568849;[Ala17]-MCH;AZD1979;ALB-127158(a);ATC0175;MCH(human, mouse, rat);BMS-819881;MCHR1 antagonist 1;MCHR1 antagonist 2;Ethyl linolenate;Melanin Concentrating Hormone, salmon;SNAP 94847;GW-803430;MCH-1 antagonist 1;NGD-4715;MCHR1 antagonist 3;TC-MCH 7c;Ac-hMCH(6-16)-NH2;Neuropeptide EI, rat;BMS-814580
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