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Spiperone hydrochloride
CAS No. : 2022-29-9
Biological Activity：Spiperone hydrochloride (Spiroperidol hydrochloride) is a selective dopamine D2 receptor (Ki values of 0.06 nM, 0.6 nM, 0.08 nM, ~350 nM, ~3500 nM for D2, D3, D4, D1 and D5 receptors, respectively) and 5-HT2A/5-HT1A receptor (Kis of 1 nM/49 nM) antagonist. Spiperone hydrochloride is also a selective α1B-adrenoceptor antagonist. Spiperone hydrochloride activates calcium-activated chloride channel (CaCC). Antipsychotic and anti-inflammatory activities[2][3][4][5].
Research Area：Inflammation/Immunology|Neurological Disease
Targets：Dopamine Receptor|Adrenergic Receptor|Chloride Channel|5-HT Receptor
Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Immunology/Inflammation Compound Library;Membrane Transporter/Ion Channel Compound Library;Neuronal Signaling Compound Library;Pyroptosis Compound Library;Neurotransmitter Receptor Compound Library;Anti-Alzheimer’s Disease Compound Library;Anti-Parkinson’s Disease Compound Library;Neurodegenerative Disease-related Compound Library;Antidepressant Compound Library;5-HT Receptor Compound Library; Human Metabolite Library;Coagulation and Anti-coagulation Compound Library;
Related Small Molecules:F 13714;Alizapride hydrochloride;Thioproperazine;Mosapride-d5;Todralazine;Bromopride-d3;ARC 239 dihydrochloride;Nuciferine;Yohimbine;Glaucine;Salbutamol;Renzapride;SB-277011 dihydrochloride;BI-167107;LY 344864 racemate;Harmine hydrochloride;Talibegron hydrochloride;MIF-1 TFA;Valerenic acid
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
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