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SP600125
CAS No. : 129-56-6
Biological Activity：SP600125 is an orally active, reversible, and ATP-competitive JNK inhibitor with IC50s of 40, 40 and 90 nM for JNK1, JNK2 and JNK3, respectively. SP600125 is a potent ferroptosis inhibitor. SP600125 inhibits autophagy and activates apoptosis[2][3].
Research Area：Cancer
Targets：Ferroptosis|Autophagy|Apoptosis|JNK
Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;MAPK Compound Library;Anti-Cancer Compound Library;Autophagy Compound Library;Reprogramming Compound Library;Oxygen Sensing Compound Library;Ferroptosis Compound Library;Orally Active Compound Library;Anti-Parkinson’s Disease Compound Library;Anti-Obesity Compound Library;Transcription Factor-Targeted Library;Antidepressant Compound Library;Human Metabolite Library;Anti-Pulmonary Fibrosis Compound Library;
Related Small Molecules:Physalin A;Bomedemstat ditosylate;Akt/NF-κB/JNK-IN-1;CIL56;DB0614;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;JNK3 inhibitor-2;Lobetyolin;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Ciclopirox-d11;Mangiferin;Cambinol;Antioxidant agent-5
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