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PFI-2 hydrochloride

CAS No. : 1627607-87-7

Biological Activity：PFI-2 ((R)-PFI-2 hydrochloride) hydrochloride is a potent and selective SET domain containing lysine methyltransferase 7 (SETD7) inhibitor. (R)-PFI-2 shows high inhibiting activity with IC₅₀ value of 2.0  nM and (S)-PFI-2 shows inhibiting activity with IC₅₀  value of 1.0  μM. PFI-2 hydrochloride can be used for the research of chronic kidney disease and inflammation response in the development of renal fibrosis^[2].

Research Area：Cancer|Infection|Inflammation/Immunology

Targets：Histone Methyltransferase

Related Screening Libraries:Bioactive Compound Library Plus;Anti-Infection Compound Library;Epigenetics Compound Library;Immunology/Inflammation Compound Library;Histone Modification Research Compound Library;Anti-Cancer Compound Library;Reprogramming Compound Library;Chemical Probe Library;Anti-Blood Cancer Compound Library;Targeted Diversity Library;

Related Small Molecules:EEDi-5285;EZH2-IN-2;BIX-01294;SGC707;(S)-HH2853;G9a-IN-1;UNC4976;MS1943;OTS186935 hydrochloride;MS8815;(R)-HH2853;EPZ020411;Furamidine dihydrochloride;EZH2-IN-12;UNC0642;MU1656;Chaetocin;UNC0646;UNC0224;MRK-740;SMYD2-IN-1;PRMT5-IN-21;Sinefungin;MM-401;SETDB1-TTD-IN-1;Dot1L-IN-2;PRMT5-IN-10;PRMT1-IN-1

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