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P62-mediated mitophagy inducer
CAS No. : 1809031-84-2
Biological Activity：P62-mediated mitophagy inducer (PMI) is a P62-mediated mitophagy activator. P62-mediated mitophagy inducer activates mitochondrial autophagy without recruitment of Parkin or collapse of the mitochondrial membrane potential and remains active in cells lacking a fully functional PINK1/Parkin pathway. P62-mediated mitophagy inducer serves as a pharmacological tool to study the molecular mechanisms of mitosis, avoiding toxicity and some of the non-specific effects associated with the sudden dissipation of mitochondria lacking membrane potential.
Research Area：Cancer|Neurological Disease
Targets：Autophagy|Mitophagy
Related Screening Libraries:Bioactive Compound Library Plus;Anti-Cancer Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Mitochondria-Targeted Compound Library;Targeted Diversity Library;
Related Small Molecules:Curcumin;Melatonin-d3;Resveratrol;Clioquinol;Betulinic acid;Matrine;Sulfosuccinimidyl oleate;Hemin;Polydatin;AICAR;ABT 737-d8;Parthenolide;D-Glutamine;Aspirin;Salicylic acid-d6
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
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