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NW 1028
CAS No. : 2749599-78-6
Biological Activity：NW 1028 is a potent VCP/p97 inhibitor. NW 1028 targets the ND1L domain of p97 and inhibits the degradation of a p97-dependent reporter. NW 1028 has good binding affinity with Kd values of 100 and 285 nM for ND1L and full length p97, respectively. NW 1028 has the function of regulating the mitotic spindle of cells.
Research Area：Cancer
Targets：p97
Related Small Molecules:DBeQ;NMS-859;NMS-873;MSC1094308;UPCDC-30245;ML240;VCP/p97 inhibitor-1;CB-5339;CB-5083;ML241 hydrochloride;Eeyarestatin I
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