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NoxA1ds TFA
Biological Activity:NoxA1ds TFA is a potent and selective NADPH oxidase 1 (NOX1) inhibitor (IC50=20 nM). NoxA1ds TFA exhibits selectivity for NOX1 over NOX2, NOX4, NOX5 and xanthine oxidase. NoxA1ds TFA inhibits NOX1-derived O2- production in HT-29 human colon cancer cells. NoxA1ds TFA attenuates VEGF-induced human pulmonary artery endothelial cell migration under hypoxic conditions in vitro.
Targets:NADPH Oxidase
Related Small Molecules:GKT136901;VAS2870;APX-115 free base;VAS 3947;NoxA1ds;Diphenyleneiodonium chloride;GSK2795039;Setanaxib;Mulberrofuran G;Fulvene-5;Fluoflavine;GLX351322;ML171
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