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KL-11743
CAS No. : 1369452-53-8
Biological Activity：KL-11743 is a potent, orally active, and glucose-competitive inhibitor of the class I glucose transporters, with IC50s of 115, 137, 90, and 68 nM for GLUT1, GLUT2, GLUT3, and GLUT4, respectively. KL-11743 specifically blocks glucose metabolism. KL-11743 can synergize with electron transport inhibitors to induce cell death[2][3].
Research Area：Cancer|Metabolic Disease
Targets：GLUT
Related Screening Libraries:Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound Library;Anti-Cancer Compound Library;Anti-diabetic Compound Library;Ferroptosis Compound Library;Glycolysis Compound Library;Orally Active Compound Library;Glutamine Metabolism Compound Library;Anti-Lung Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Glucose Metabolism Compound Library;
Related Small Molecules:Sennidin A;Licarin B;GLUT4 activator 1;GLUT4-IN-2;STF-31;KPH2f;BAY-876;MOTS-c(human) acetate;Phloretin;GLUT inhibitor-1;4,6-O-Ethylidene-α-D-glucose;WZB117;GLUT1-IN-1;SW157765;Lavendustin B;Avicularin;Rhoifolin;Fasentin;GLUT1-IN-2;DRB18
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