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JZL 184
CAS No. : 1101854-58-3
Biological Activity:JZL 184 is a potent, selective and irreversible MAGL inhibitor that blocks 2-Arachidonoylglycerol (2-AG) hydrolysis in brain membranes (IC50 of 8 nM). JZL 184 displays >300-fold selectivity for MAGL over FAAH[2].
Research Area:Neurological Disease
Targets:MAGL
Related Screening Libraries:Covalent Screening Library Plus;Bioactive Compound Library Plus;Metabolism/Protease Compound Library;Covalent Screening Library;Anti-Cancer Metabolism Compound Library;Lipid Metabolism Compound Library ;Human Metabolite Library;
Related Small Molecules:MAGL-IN-6;PF-06795071;JZL195;N-Arachidonyl maleimide;ML-226;JW 642;WWL123;Euphol;ABX-1431;JJKK 048;LEI-106;SAR629;DO-264;FAAH-IN-5;ABD957;JZP-361;MGL-IN-1;JZP-430;KT109;FAAH/MAGL-IN-2;Monoacylglycerol lipase inhibitor 1;KT182;SA57;FAAH/MAGL-IN-1;KML29;ML-211;MJN110;KT185;WWL70;MAGL-IN-5
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