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Isofraxidin
CAS No. : 486-21-5
Biological Activity：Isofraxidin, a coumarin component from Acanthopanax senticosus, inhibits MMP-7 expression and cell invasion of human hepatoma cells. Isofraxidin inhibits the phosphorylation of ERK1/2 in hepatoma cells. Isofraxidin attenuates the expression of iNOS and COX-2, Isofraxidinalso inhibits TLR4/myeloid differentiation protein-2 (MD-2) complex formation[2].
Research Area：Inflammation/Immunology
Targets：MMP|Toll-like Receptor (TLR)|COX
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Related Small Molecules:C29;Akt/NF-κB/JNK-IN-1;COX-2/5-LOX-IN-3;TMX-201;WAY-170523;CTTHWGFTLC, CYCLIC;RS 09;Ampyrone;Edaravone;ODN 20844;COX-2-IN-24;D-Isofloridoside;TLR7/8-IN-1;TLR8 agonist 5;Zaltoprofen-d7;α-Vitamin E-d6;1-Hydroxy-ibuprofen;Chondroitin sulfate;Asaraldehyde;Sulfo-ara-F-NMN;TLR7/8 antagonist 1;(-)-Epicatechin;Ginsenoside F4;20(S)-Ginsenoside Rg3;Ginsenoside Rd;Gardiquimod;PF-4878691
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